2023FA - Adv. Nucleic Acids DNA MBGC5071
10/23/2023-12/21/2023 Monday 1:30-3:15 PM, Tuesday, 9:45-11:30 AM
Location: ICPH-E220R unless notified
Advances in nucleic acid research; from basic principle to pathogenesis (including cancer development, immune response to infectious diseases, neurological disorder)
The course overviews various topics under the following categories: chemistry and synthetic biology; computational biology; gene regulation, chromatin and epigenetics; genome integrity, DNA repair and replication; genomics; nucleic acid enzymes; structural biology.
1. DNA replication in eukaryotes
2. DNA damage repair,
DNA double strand break (DSB) repair
3. DNA sequencing method and data analysis
4. Telomeres; aging and cancer development
5. Epigenetic regulation of DNA replication, centromere
6. Trypanosoma: gene rearrangement and escaping from immune response